Dapoxetine is the active ingredient itself present in the products called Priligy. The mechanism of action of Dapoxetine in premature ejaculation is supposed to be associated to the suppression of neuronal reuptake of serotonin and the successive increase in the effect of the neurotransmitter's action at pre- and post-synaptic receptors. Dapoxetine is known to inhibit the ejaculatory expulsion reflex by acting at a supraspinal level at the specific brain structure for the effect. The neurons that innervate the seminal vesicles, vas deferens, prostate, bulbourethral muscles, and bladder neck cause them to contract in a coordinated fashion to achieve ejaculation. It is known that Dapoxetine might regulate this ejaculatory reflex causing an increase in pudendal motoneuron reflex discharge (PMRD) latency and a reduction in PMRD duration causing a delay in ejaculation.