Generic Loratadine comprises of Loratadine as an active ingredient which belongs to the pharmacological class of tricyclic antihistamines.
Loratadine, the active element in this medication is a long-acting tricyclic antihistamine which prevents the actions of a biochemical mediator called histamine, a chemical which is a controller of allergic reactions in the body. When the body is exposed to any foreign material or an allergen, immune system of the body gets activated to release histamine which exhibits its actions by binding to histamine receptors on the cells. This leads to allergy symptoms like sneezing, rashes and other skin reactions. Loratadine prevents the actions of the histamine and does not allow histamine to exhibit any allergic reaction; thus, preventing from the allergy. It is a second generation H1-antihistamine which has a very less ability to cross the brain and hence, has less potential of including drowsiness and is therefore, categorized as a non-sedating anti-histaminic agent. Loratadine is usually indicated for the symptomatic relief of allergy including hay fever (allergic rhinitis), urticaria (hives); either short or long term and other skin allergies. For allergic rhinitis (hay fever), loratadine is effective for both nasal and eye symptoms which include sneezing, runny nose, itchy and burning eyes. Besides this, loratadine resolves the itching due to Kimura's disease.