Duratia 90mg-Last Long in bed without ejaculating

Duratia 90 mg contains dapoxetine, a selective serotonin reuptake inhibitor (SSRI) designed specifically for premature ejaculation (PE) treatment. It works by modulating the central nervous system to enhance control over ejaculation and delay the ejaculatory reflex.

Mechanism of Action

Serotonin Modulation

Dapoxetine increases serotonin levels in the brain by inhibiting its reuptake into nerve cells. Serotonin is a neurotransmitter. It plays a key role in controlling the ejaculatory reflex. Higher serotonin levels enhance communication between nerve cells, helping to delay ejaculation.

Impact on the Ejaculatory Reflex

The sacral spinal reflex center, regulated by the brain, controls the ejaculatory reflex. By increasing serotonin activity, dapoxetine delays the signals sent from the brain to the spinal cord that trigger ejaculation. It results in greater control over the timing of ejaculation and extends the duration of sexual activity.

On-Demand Effectiveness

Take Duratia 90 mg 1-3 hours before sexual activity, allowing dapoxetine to be at peak levels when needed. Its action is temporary and provides relief only during the effective window of the medication (typically 4-6 hours).

How It Helps with Premature Ejaculation

Increases Intravaginal Ejaculatory Latency Time (IELT): IELT refers to the time between penetration and ejaculation. Dapoxetine significantly increases IELT, helping men last longer during intercourse.

Improves Ejaculatory Control

It helps men feel more in control of their ejaculation timing, reducing anxiety and stress related to performance.

Enhances Sexual Satisfaction

Longer duration of intercourse can improve satisfaction for both partners, boosting confidence and overall relationship quality.

Severe PE Cases

The higher dose (90 mg) is ideal for men who do not achieve sufficient results with lower doses (30 mg or 60 mg).

Combination Therapy

You can use it with ED medications under medical guidance for men experiencing both PE and ED. By modulating serotonin levels in the brain, Duratia 90 mg provides an on-demand solution for men struggling with premature ejaculation, enhancing sexual performance and satisfaction. Always consult a healthcare provider for personalized advice.

How to Take Duratia 90 mg

Take one tablet 1-3 hours before planned sexual activity. It allows the medication to reach peak effectiveness during the desired time window. Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet, as this may affect the absorption of the medication. You can administer Duratia with or without meals. Avoid Heavy, Greasy, or Fatty Meals. High-fat meals may slightly delay absorption, reducing the medication's effectiveness.

Avoid Alcohol

Do not consume alcohol while taking Duratia, as it can increase the risk of side effects like dizziness, drowsiness, or impaired judgment.

One tablet per day is the maximum dose. Do not take more than one tablet within 24 hours to avoid the risk of overdose or increased side effects.

Duratia (Dapoxetine) Doses

1. Duratia 30 mg

It is the starting dose for men who are new to dapoxetine, those with mild PE symptoms, and first-time users to assess how their body responds to the medication and individuals with fewer side effects concerns. It minimizes the risk of side effects while offering effective results.

2. Duratia 60 mg

It is the standard dose for most men with moderate-to-severe PE, who need a potent dose higher than 30 mg to achieve the desired results. It provides consistent control over ejaculation for most users.

3. Duratia 90 mg

It is the maximum dose for men who do not respond adequately to lower doses and men with severe PE or those unresponsive to 30 or 60 mg. It offers potent effects, with prolonged control over ejaculation.

Choosing the Right Dose

For First-Time Users

Start with 30 mg to assess tolerance and effectiveness. Your doctor may increase the dose to 60 or 90 mg if needed.

For Severe PE

Doctors may prescribe Duratia 90 mg for men who do not achieve satisfactory results with lower doses.

For Sensitive Individuals

Begin with the lowest dose (30 mg) to reduce the likelihood of side effects.

Hydration: Drink plenty of water when taking Duratia to reduce the risk of side effects such as nausea or dizziness.

1. Medical Conditions

Heart Conditions

Avoid if you have a history of severe heart problems:

• Heart failure.
• Arrhythmia (irregular heartbeat).
• Significant heart valve disease.
• Recent heart attack or stroke.

Use it cautiously if you have mild or well-managed cardiovascular conditions.

Liver or Kidney Impairment

Dose adjustments may be necessary for individuals with moderate-to-severe liver or kidney issues.

Seizure Disorders

Not for individuals with a history of epilepsy or uncontrolled seizures.

Mental Health Conditions

Avoid if you have a history of bipolar disorder, mania, or severe depression. Use it cautiously if you have mild or well-controlled anxiety or depression.

Blood Pressure Issues

Avoid if you have low blood pressure (hypotension). Use it cautiously if you are on medications for high blood pressure, as Duratia can cause dizziness or fainting.

Bleeding Disorders

Inform your doctor if you have a history of bleeding disorders, as dapoxetine may increase the risk of bleeding, especially if combined with medications like aspirin or blood thinners.

2. Drug Interactions

Nitrates

Do not take Duratia with nitrate medications (e.g., nitroglycerin) used for chest pain, as this can cause a dangerous drop in blood pressure.

Other SSRIs or Antidepressants

Avoid combining Duratia with other selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs), as it may increase the risk of serotonin syndrome.

MAO Inhibitors

Do not take Duratia if you have used a monoamine oxidase inhibitor (MAOI) within the past 14 days, as this may trigger severe side effects.

Alcohol

Avoid alcohol while taking Duratia, as it can exacerbate side effects like dizziness, drowsiness, and fainting.

Blood Thinners

Use it cautiously if you are taking blood thinners like warfarin or antiplatelet drugs, as it may increase the risk of bleeding.

Driving and Operating Machinery

Avoid driving or operating heavy machinery after taking Duratia, as it may cause dizziness, drowsiness, or fainting.

Hydration

Drink plenty of water when taking Duratia to reduce the risk of nausea or dizziness.

High-Risk Activities

Avoid situations where sudden dizziness or fainting could pose a safety risk (e.g., climbing heights or swimming).

Follow Prescribed Dose

Do not exceed the recommended dose of one tablet (90 mg) in 24 hours. Overdosing may increase the risk of severe side effects.

Older Individuals

Older men may require closer monitoring because of the potential sensitivity to side effects.

Pregnancy and Breastfeeding

Not for use by women, especially during pregnancy or breastfeeding.

Children and Adolescents

Not suitable for individuals under 18 years of age.

• Nausea
• Dizziness
• Headache
• Dry Mouth
• Insomnia
• Fatigue
• Sweating
• Diarrhea

• Severe Dizziness or Fainting
• Allergic Reactions (Anaphylaxis)
• Serotonin Syndrome
• Irregular Heartbeat
• Seizures
• Persistent or Worsening Anxiety
• Difficulty Breathing
• Suicidal Thoughts or Behaviors

How long does it work?

It takes 1-3 hours to kick in after ingestion. The effects last for about 4-6 hours, providing sufficient time for planned sexual activity.

How do you minimize side effects?

Take Duratia 90 mg exactly as prescribed by your doctor. Avoid alcohol, as it can worsen side effects like dizziness and drowsiness. Stay hydrated and eat light meals before taking the medication. Stand up slowly from sitting or lying positions to prevent dizziness.

What are the risk factors for severe side effects?

If you have pre-existing conditions, such as heart problems, epilepsy, mental health conditions, severe liver or kidney impairments, or drug interactions, such as taking Duratia with alcohol, SSRIs, MAO inhibitors, or other serotonergic drugs, increases the risk of serotonin syndrome or cardiovascular issues. If you overdose, exceeding the prescribed dose raises the likelihood of severe side effects.

When do you need emergency help?

Seek immediate medical attention if you experience chest pain, irregular heartbeat, difficulty breathing, signs of an allergic reaction (swelling, rash, or difficulty breathing), symptoms of serotonin syndrome (confusion, rapid heartbeat, fever, or tremors), or fainting or persistent dizziness that does not improve.

How do you manage the risks associated with Duratia 90mg?

Use Duratia only as prescribed by your healthcare provider. Avoid alcohol and other contraindicated medications. Inform your doctor of any pre-existing conditions or medications you are currently taking.