How Avanafil (200 mg) Treats Erectile Dysfunction?
It is a Phosphodiesterase type 5 (PDE5) inhibitor. It enhances cGMP Levels crucial for erection. Avanafil blocks the PDE5 enzyme, which degrades cyclic guanosine monophosphate (cGMP). CGMP relaxes smooth muscle cells and dilates blood vessels in the penis. The relaxed blood vessels allow more blood to flow into the corpora cavernosa, the spongy tissues of the penis. During sexual stimulation, the increased blood flow results in a firm and sustained erection.
Advantages of Avanafil
Rapid Onset: Avanafil works within 15-30 minutes, faster than Sildenafil or Tadalafil.
Selective action: selective for PDE5, leading to fewer side effects like headaches and nasal congestion.
Long-Lasting Effects: Provides erection support for up to 6-8 hours, offering flexibility for planned sexual activity.
How Dapoxetine (60 mg) Treats Premature Ejaculation?
It is a selective serotonin reuptake inhibitor (SSRI). It delays the ejaculatory urges by increasing the Serotonin levels in the brain. Dapoxetine inhibits the reuptake of serotonin, a neurotransmitter that plays a key role in the ejaculatory reflex. Higher serotonin levels improve communication within the sacral spinal reflex center, delaying ejaculation. It delays the ejaculatory reflex by regulating serotonin. Dapoxetine increases Intravaginal Ejaculatory Latency Time (IELT), extending the duration of intercourse. It improves ejaculatory control, reduces anxiety, and enhances confidence by providing better control over ejaculation.
Onset: Dapoxetine works within 1-3 hours of ingestion.
Duration: Effects last up to 4-6 hours by aligning with the effects of Avanafil.
- Avanafil ensures strong and reliable erections by increasing blood flow to the penis during sexual stimulation that supports prolonged intercourse.
- Dapoxetine delays ejaculation, allowing for extended sexual activity and greater satisfaction.
- Avanafil starts working in 15-30 minutes, making it one of the fastest-acting ED treatments.
- Dapoxetine ensures ejaculatory control within 1-3 hours, offering sufficient preparation time.
- Avanafil provides erection support for 6-8 hours.
- Dapoxetine ensures ejaculatory control for 4-6 hours, ensuring a firm erection and prolonged control over ejaculation.