How Tadalafil Works (Treats ED)
Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor that enhances blood flow to the penis, enabling strong and sustained erections during sexual stimulation.
Boosting cGMP Levels
During sexual arousal, the body releases nitric oxide (NO) in the penile tissues. NO activates an enzyme called Guanylate Cyclase, which increases the production of cyclic guanosine monophosphate (cGMP). CGMP relaxes the smooth muscles in the blood vessel walls, dilating the blood vessels and improving blood flow to the penis.
Role of PDE5
PDE5 is an enzyme that breaks down cGMP, reducing blood flow and causing the erection to subside.
Tadalafil’s Role
Tadalafil inhibits the PDE5 enzyme, preventing the breakdown of cGMP.
It helps maintain high cGMP levels, ensuring sustained blood vessel relaxation and consistent blood flow during sexual stimulation.
How Dapoxetine Works (Treats PE)
Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) that delays ejaculation by modulating serotonin activity in the brain.
Serotonin and Ejaculation Control
Serotonin plays a critical role in the spinal ejaculatory reflex, which regulates the ejaculation timing. Low serotonin activity in specific brain pathways can lead to premature ejaculation.
Dapoxetine's Role
Dapoxetine increases serotonin levels in the synaptic cleft (the space between nerve cells), preventing the ejaculatory signals from communicating between the neurons. This strengthens the control of the spinal ejaculatory reflex, delaying ejaculation and prolonging sexual activity.
Combined Effect of Tadalafil + Dapoxetine
Tadalafil Role (ED)
Improves blood flow to the penis, ensuring strong and long-lasting erections during sexual arousal.
Dapoxetine Role (PE)
Increases serotonin activity, delaying the ejaculatory reflex and extending the duration of sexual activity.
Synergistic Effect
By addressing both ED and PE, Super Tadarise enhances overall sexual performance, confidence, and satisfaction.
Steps after Taking Super Tadarise
Within 30-60 minutes, Tadalafil starts by increasing cGMP levels and improving blood flow to the penis. Within 1-2 hours, Dapoxetine modulates serotonin levels, delaying ejaculation and enhancing control.
During Sexual Activity
Tadalafil ensures a firm and lasting erection during arousal. Dapoxetine prolongs the time to ejaculation, leading to more satisfying and extended sexual encounters.
After Sexual Activity
Dapoxetine effects wear off after the sexual activity is complete.
Tadalafil remains active for up to 36 hours, providing additional opportunities for intimacy without re-dosing.