Tadaga 36 hours of erection when aroused

Tadaga 60mg, which contains tadalafil as its active ingredient, works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5). PDE5 prevents a man from achieving a sturdy and sustainable erection. The PDE5 enzyme can reduce blood flow to the penis, preventing the ability to achieve or maintain an erection.

Tadaga 60mg Action Mechanism

When sexual arousal occurs, our body releases nitric oxide (NO) into the erectile tissue of the penis. NO stimulates the production of cGMP, which relaxes the smooth muscles and allows blood to flow more freely into the penile arteries.

Tadaga 60 mg inhibits and slows the PDE-5 effect on the erectile tissues (corpus cavernosum) of the penile region. By blocking PDE 5 in men with erectile dysfunction (ED), Tadaga 60 mg prevents it from breaking down and hydrolyzing cyclic guanosine monophosphate (cGMP) molecules.

CGMP molecules induce vasodilation (widening of blood vessels). Increasing cGMP Levels is vital for erection. CGMP relaxes the smooth muscles of the blood vessels in the erectile tissues.

Tadaga 60mg can maintain an erection for a longer duration. With increased cGMP levels, the smooth muscles in the blood vessels of the penis remain relaxed, allowing sustained blood flow. It helps to achieve and maintain an erection long enough for satisfactory sexual activity.

Prolonged Action

Tadalafil has a longer half-life than many other ED drugs, meaning it stays effective for up to 36 hours. It allows for more spontaneous and flexible timing around sexual activity compared to drugs that have a shorter window of effectiveness.

Eases BPH Symptoms

It relieves the symptoms of BPH. By relaxing smooth muscles, Tadaga relieves urinary symptoms in men with benign prostatic hyperplasia (BPH), such as difficulty starting urination, weak stream, and frequent need to urinate.

Tadaga (tadalafil) is available in various doses to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH), depending on individual needs and medical conditions.

Typical Dosages for Tadaga 10mg or 20mg

Occasional Use (As Needed)

• Starting Dose: 10mg taken about 30 minutes before sexual activity.
• Dose Adjustments: Doctors may increase it to 20mg or decrease it to 5mg based on effectiveness and tolerance.
• Frequency: Only one dose per 24 hours.
• Duration: Effective for up to 36 hours, allowing flexibility and spontaneity.

Tadaga 5mg for Daily Use (Low-Dose):

• Taken once daily, usually around the same time each day.
• Suitable for men engaging in frequent sexual activity several times a week.

Tadaga 2.5mg Lowest Daily Dose

Used for men who need daily support for ED but may experience side effects at higher doses.

Tadaga 40mg or 60mg for Severe Cases of ED

Sometimes prescribed for men who do not respond well to lower doses.

Frequency: Take it as needed but not recommended daily, one dose per 24 hours.

Special Consideration: Higher doses should only be under medical supervision because of the increased risk of side effects.

Dosage for BPH

Tadaga 5mg Once Daily

This dose is effective for BPH symptoms, as it helps relax smooth muscles in the bladder and prostate. Doctors may prescribe it for men who experience both ED and BPH symptoms.

Swallowing the Tablet

Swallow the tablet whole with a glass of water. Avoid crushing or splitting it, as it may affect absorption and effectiveness. Take Tadaga 30 minutes to an hour before sexual activity to allow it time to start.

It remains effective for up to 36 hours, giving flexibility to the timing of sexual activity. Tadaga only works with sexual arousal, so natural stimulation is necessary to achieve an erection.

Usage Guidelines

• Timing: For as-needed doses (10mg, 20mg, 40mg, or 60mg), take Tadaga about 30 minutes before sexual activity.
• With or Without Food: You can take it with or without food, though a high-fat meal may delay absorption. However, a high-fat meal may delay the absorption, potentially delaying its onset of action.
• Maximum Dosage: Do not exceed one dose per 24-hour period to avoid potential side effects. 

Determine Your Dose Based on Usage

• As-Needed Use: For ED, if you are using Tadaga occasionally, take the prescribed dose (10mg, 20mg, 40mg, or 60mg) about 30 minutes before sexual activity.
• Daily Use: For daily dosing (usually 2.5mg or 5mg). You may take it daily to maintain a steady level in your system. Daily doses are suitable if you have frequent sexual activity or to treat both ED and BPH. 

Avoid Alcohol and Grapefruit Products

• Limit Alcohol: Excessive alcohol can increase the risk of side effects such as dizziness or low blood pressure, so limit or avoid it when taking Tadaga.

Avoid Grapefruit: Grapefruit and grapefruit juice can interact with tadalafil, affecting the metabolism of the drug and may increase side effects.

Disease interactions with Tadaga 60mg

Severe Heart Disease: People with unstable angina, recent heart attacks (within the past 90 days), or severe heart failure should avoid Tadaga.

Uncontrolled Hypertension or Hypotension: Tadaga can lower blood pressure. Patients with high or low blood pressure must avoid it.

Recent Stroke: Individuals who have had a stroke in the last six months should avoid Tadaga because of the increased risk of cardiovascular complications.

Nitrate Medications

Tadaga should not be taken by those on nitrate medications (e.g., nitroglycerin) commonly used to treat chest pain or angina. Combining tadalafil with nitrates can cause a significant and dangerous drop in blood pressure.

Liver Disease

Individuals with severe liver impairment may not metabolize tadalafil effectively, leading to increased side effects.

Kidney Disease

For those with severe kidney disease or those on dialysis, they must avoid Tadaga 60mg or 40mg or adjust the dose and monitor carefully.

Eye Disease

Retinitis Pigmentosa-A rare genetic eye condition that may worsen further with Tadaga 60mg usage.

Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)-A history of this condition increases the risk of sudden vision loss, a severe side effect of Tadaga 60mg.

Bleeding Disorders

Individuals with bleeding disorders (e.g., hemophilia) may have an increased risk of bleeding with Tadaga.

Sickle Cell Anemia, Multiple Myeloma, and Leukemia

Tadaga 60mg may aggravate these blood disorders and could increase the risk of prolonged and painful erections (priapism).

Peptic Ulcers and Active Stomach Ulcers

Tadaga may exacerbate gastrointestinal symptoms in people with active peptic ulcers, potentially increasing the risk of bleeding.

Deformities of the Penis

Anatomical Deformities

Tadaga 60mg may worsen Peyronie’s disease (abnormal curvature) and increase the risk of priapism (prolonged erection).

Allergy to Tadalafil or Similar Compounds

Anyone with known hypersensitivity or allergic reactions to tadalafil or other PDE5 inhibitors should avoid Tadaga.

Drug interactions with Tadaga 60mg

Nitrate Medications

Examples: nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and recreational drugs called “poppers” (amyl nitrate or butyl nitrate).

Risk: Combining tadalafil with nitrates can cause a severe and potentially life-threatening drop in blood pressure. It is one of the strongest contraindications for tadalafil and similar ED medications.

Alpha-Blockers

Examples: These are doxazosin, tamsulosin, terazosin, and prazosin, often prescribed for high blood pressure or prostate issues.

Risk: Combining tadalafil with alpha-blockers can also cause a significant drop in blood pressure, leading to dizziness, fainting, and potential cardiovascular complications. If you need both drugs, take them under medical supervision, often with dose adjustments.

Certain Antifungal and Antibiotic Medications

Antifungal Examples: Ketoconazole, Itraconazole.

Antibiotic Examples: Erythromycin and Clarithromycin.

Risk: These medications can inhibit the metabolism of tadalafil, leading to higher levels of the drug in the body and an increased risk of side effects. You either adjust the dose or carefully monitor it.

HIV Protease Inhibitors

Examples: Ritonavir, saquinavir, atazanavir.

Risk: Protease inhibitors can increase tadalafil levels and the likelihood of side effects. Doctors may recommend a lower tadalafil dose or suggest avoiding it altogether.

Other PDE5 Inhibitors

Examples: The PDE-5 inhibitors are sildenafil, vardenafil, and avanafil.

Risk: Combining tadalafil with other PDE5 inhibitors can increase the risk of side effects, including low blood pressure, vision problems, and priapism (prolonged erections). You can take one PDE5 inhibitor at a time.

Antihypertensive Medications

Examples: The specific blood pressure medications are alpha-blockers, beta-blockers, and riociguat.

Risk: They may interact with tadalafil and increase the risk of hypotension (low blood pressure). Use antihypertensive drugs with extra caution when combining them, especially with high doses of tadalafil.

CYP3A4 Inhibitors

Examples: Avoid ulcer and acid reflux medication cimetidine and grapefruit juice.

Risk: CYP3A4 inhibitors can slow the breakdown of tadalafil, leading to prolonged drug effects and increased side effects. Avoid grapefruit consumption and medications like cimetidine, or take it cautiously.

Epilepsy Medications (Certain Anticonvulsants)

Examples: These are carbamazepine, phenytoin, and phenobarbital.

Risk: These medications may reduce tadalafil levels in the blood, potentially making it less effective. You need to adjust the dose.

Other Drugs Metabolized by CYP3A4 Enzyme

CYP3A4 enzyme metabolizes Tadaga 60mg, so avoid the drugs affecting the functions of this enzyme that could interact.

Headache: A common side effect because of the dilation of blood vessels, which can sometimes lead to mild-to-moderate headaches.

Flushing: Many people experience warmth or redness in the face, neck, or chest after taking Tadaga 60mg because of the increased blood flow.

Indigestion or Upset Stomach: Tadalafil can cause mild stomach discomfort, acid reflux, or indigestion.

Back Pain and Muscle Aches: Some people report back pain or general muscle aches, typically occurring 12 to 24 hours after taking tadalafil. The aches usually subside on its own within a few days.

Nasal Congestion or Runny Nose: Mild nasal congestion or a stuffy nose because of blood vessel dilation in the nasal passages.

Dizziness: Tadalafil can lower blood pressure, which may cause mild dizziness, especially when standing up too quickly.

Vision Changes: Some users report temporary changes in vision, such as a blue tinge, blurred vision, or increased sensitivity to light. It is rare but can occur because of tadalafil's effect on PDE6 enzymes in the retina.

Priapism (Prolonged Erection): Though very rare, priapism (an erection lasting longer than 4 hours) is a severe side effect that requires immediate medical attention to prevent damage to the penis.

Nausea: Some individuals may experience mild nausea after taking tadalafil if taken on an empty stomach.

Skin Rash: In rare cases, users may develop a mild skin rash.

Severe Allergic Reactions: If you notice swelling of the face, lips, tongue, or throat, difficulty breathing, or hives, seek immediate medical help, as these may be life-threatening allergic reactions.

Priapism (Prolonged Erection): An erection lasting over four hours can cause permanent damage to the penile tissue. Priapism is a medical emergency. If you experience an erection that persists for over four hours, go to the emergency room immediately.

Severe Vision Loss (NAION): A sudden vision loss in one or both eyes called Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION). Stop taking tadalafil and seek urgent medical attention if you experience sudden vision loss. It may be irreversible.

Hearing Loss or Ringing in the Ears: A sudden decrease or loss of hearing, sometimes accompanied by ringing in the ears (tinnitus) or dizziness. Discontinue use and seek medical attention if you experience hearing loss, as it could be permanent if not treated promptly.

Chest Pain or Heart Attack Symptoms: Chest pain, pressure, pain radiating to the arm or shoulder, sweating, and nausea. If chest pain occurs, especially during sexual activity, stop and seek emergency medical care.

Severe dizziness or fainting: It may cause a significant drop in blood pressure levels, leading to severe dizziness, fainting, or light-headedness. If you feel faint, get medical help, especially if the dizziness persists.

Shortness of Breath or Breathlessness: Trouble breathing, especially with chest discomfort, is a severe reaction. Seek medical attention immediately if you experience breathing difficulties.

Irregular Heartbeat (Arrhythmia): Some people may experience palpitations or an abnormal heart rhythm, which can be dangerous. Consult a doctor if you notice irregular heartbeats, especially if accompanied by other symptoms like chest pain or dizziness.

Severe Skin Reaction: If you notice blistering, peeling skin, rash, and/or painful sores in the mouth or other mucous membranes, these could be Stevens-Johnson syndrome or another severe skin reaction requiring immediate medical care.

How long does Tadaga 60mg last?

Popularly called The Weekend Pill, it can last for 36 hours but varies from person to person.

When should I take Tadaga 60mg?

Doctors may prescribe it for men who do not respond well to lower doses like Tadaga 20mg or 40mg.

What are the advantages of Tadaga 60mg?

Tadaga 60mg is well-tolerated, with fewer side effects when taken at prescribed dosages. It is a generic version, often more affordable than branded Tadalafil variants, making it a cost-effective alternative while offering the same therapeutic effects. It can last up to 36 hours in the body, which allows more spontaneity in sexual activity.

What are the starting doses of Tadaga?

You can start with Tadaga 2.5mg, 5mg, or 10mg, taken about 30 minutes before sexual activity.

Can I use Tadaga daily?

You can administer Tadaga 2.5mg or 5mg daily. Consult your doctor for daily usage of Tadaga.