Tadora contains the same active ingredient, Tadalafil, as other ED medications, which works by inhibiting the PDE5 enzyme to improve blood flow to the penis.
Sexual Stimulation Triggers Nitric Oxide (NO) Release
Biological Process: During sexual arousal, the body releases nitric oxide (NO) in the penile tissues.
Role of Nitric Oxide (NO)
NO activates the enzyme Guanylate Cyclase, which increases cyclic guanosine monophosphate (cGMP) levels. It is critical for blood flow enhancement in the penile area for erection.
Role of cGMP
Smooth Muscle Relaxation: cGMP relaxes the smooth muscles of the corpus cavernosum (spongy tissue in the penis).
Vasodilation: Relaxed muscles allow blood vessels to dilate, increasing blood flow into the penis.
Erection Formation: The inflow of blood fills the spongy tissue, causing the penis to become erect.
PDE5 and Its Role in Erectile Dysfunction
The enzyme PDE5 breaks down cGMP, ending the erection process when sexual arousal stops.
Problem in ED: In men with ED, PDE5 activity may prevent sufficient cGMP buildup, leading to difficulty in achieving or maintaining an erection.
Action Mechanism of Tadora
PDE5 Inhibition: The active ingredient, Tadalafil, inhibits PDE5, preventing it from breaking down cGMP.
Prolonged Effect: By sustaining cGMP levels, Tadora enhances the natural erection process, making it easier to achieve and maintain an erection during sexual arousal.
Rapid Absorption: Oral ingestion causes the body to absorb Tadora 20mg into the bloodstream. It starts within 30-60 minutes, though individual response times may vary.
Half-Life: Tadalafil has a long half-life of approximately 17.5 hours, which means it remains active in the body for up to 36 hours.
Benefits: This prolonged action allows greater spontaneity, enabling men to engage in sexual activity at any time within this window without taking additional doses.
Erection Stops after Sexual Activity
Natural Process: Once sexual stimulation ends, the body naturally breaks down cGMP, and the erection subsides. Tadora does not cause continuous erections; it facilitates the natural response to sexual arousal.
Additional Benefits of Tadora 20mg
Improved Blood Flow: Tadalafil improves blood flow not just to the penis but to other parts of the body, helping other conditions like:
Benign Prostatic Hyperplasia (BPH) relieves urinary symptoms by relaxing smooth muscles in the bladder and prostate.
Pulmonary Arterial Hypertension (PAH) reduces high blood pressure in the lungs by improving blood flow.