Tazzle 20mg-Faster Action, Erection Lasting Long

Tazzle 20mg contains Tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. It works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), improving blood flow to the penile region during sexual arousal. It helps achieve and maintain an erection. Tazzle 20mg (Tadalafil) inhibits the PDE5 enzyme. PDE 5 breaks down cGMP and hinders the erection process.

Tazzle 20mg Mechanism of Action

Normal Erectile Function

During sexual arousal, the body releases nitric oxide (NO) in the erectile tissue of the penis. Nitric oxide stimulates the production of cyclic guanosine monophosphate (cGMP), a molecule that relaxes the smooth muscles and dilates the blood vessels in the penis. It allows increased blood flow into the penile tissue, causing an erection.

Role of PDE5

PDE5 is an enzyme that breaks down cGMP, which leads to reduced blood flow and erection breakdown.

How does the Tazzle 20mg work?

As a result, cGMP levels remain elevated, which keeps the smooth muscles relaxed and blood vessels dilated for longer. It ensures improved blood flow to the penile tissue during sexual stimulation, helping achieve and maintain a firm erection.

Sexual stimulation required: Tazzle 20mg will not work on its own; sexual stimulation is necessary to trigger the release of nitric oxide and kick off the erection process.

Duration of Action: Tadalafil, the active ingredient in Tazzle 20mg, has a long half-life of up to 36 hours, making it known as the "weekend pill."

Steps in the Body after Taking Tazzle 20mg

• You take Tazzle 20mg orally.
• Absorbed into the bloodstream through the gastrointestinal tract.
• Tadalafil blocks the PDE5 enzyme in the penis.
• Upon sexual stimulation, cGMP levels rise, leading to the relaxation of smooth muscles in the penile arteries.
• Increased blood flow into the penis.
• You achieve and maintain a firm erection sufficient for sexual activity.

Onset and Duration

Onset of Action: Tazzle 20mg tablets start within 30 to 60 minutes after ingestion.

Duration: It remains effective for up to 36 hours, allowing for spontaneous and natural intimacy.

Tazzle 20mg works by inhibiting the PDE5 enzyme, promoting increased blood flow to the penis during sexual arousal. Its long-lasting effects make it a preferred option for men looking for flexibility and confidence in managing erectile dysfunction.

The popular sublingual or oral disintegrating form of Tazzle allows the medication to be absorbed directly into the bloodstream through the mucous membranes, bypassing the digestive system.

Tazzle (Tadalafil) is available in various doses to treat erectile dysfunction (ED) and other related conditions, like benign prostatic hyperplasia (BPH). The correct dose depends on the severity of the condition, individual response to the medication, and the medical recommendation.

Tazzle Doses

Tazzle dosing flexibility makes it suitable for daily use and on-demand therapy, allowing patients to choose what works best for their lifestyle.

Tazzle 2.5 mg

Usage: Suitable for daily use in men who require continuous treatment for ED.

Taken once daily at the same time, regardless of sexual activity.

Ideal For: Men prefer a low-dose daily regimen for spontaneous intimacy.

Tazzle 5 mg

Usage: Take once daily, either for ED or for benign prostatic hyperplasia (BPH) symptoms.

Ideal for: Men with mild ED who benefit from daily treatment. Patients with BPH who need relief from urinary symptoms.

Tazzle 10 mg

Usage: Taken on demand, about 30-60 minutes before anticipated sexual activity.

Not intended for daily use.

Ideal For: Men with moderate ED who do not require frequent dosing.

Tazzle 20 mg

Usage: Taken on demand as needed, 30-60 minutes before sexual activity. It provides long-lasting effects for up to 36 hours.

Ideal For: Men with moderate to severe ED who require higher effects. Those who prefer flexibility over daily dosing.

Dosage Guidelines

Daily Use: Take Tazzle 2.5 mg or 5 mg once daily, preferably at the same time each day, with or without food. Daily dosing is ideal for men having frequent sexual activity.

On-Demand Use: Take Tazzle 10 mg or 20 mg 30-60 minutes before sexual activity. You must take one dose within 24 hours.

Maximum Dose: The highest recommended dose is 20 mg per day. Exceeding this can increase the risk of side effects.

Missed Dose (Daily Use)

If you miss a dose, take it as soon as you remember. Skip it if you are close to the next scheduled dose.

Choosing the Right Dose

Mild ED: Start with 2.5 mg or 5 mg daily.

Moderate ED: 10 mg on demand

Severe ED: 20 mg on demand may be more effective.

BPH Treatment: 5 mg daily

Caution: Do not take more than one dose within 24 hours. Avoid combining Tazzle with nitrate medications, as this can cause a significant drop in blood pressure.

Heart Problems

Patients with a history of heart attack, irregular heartbeat, angina, or chest pain during sexual activity must avoid Tazzle 20mg. Tadalafil can strain the heart during physical exertion, including intercourse.

Blood Pressure Issues

Severe hypotension (low blood pressure) or uncontrolled hypertension (high blood pressure).

Liver or Kidney Disease

The doctor may suggest dose adjustments for those with impaired liver or kidney function.

Eye Conditions

Patients with a history of non-arteritic anterior ischemic optic neuropathy (NAION) must avoid Tazzle 20mg because it may cause vision loss.

Bleeding Disorders or Stomach Ulcers.

Priapism History

If you have experienced priapism (prolonged erection lasting over 4 hours) in the past, you are at greater risk of this complication.

Medication Interactions

Nitrates (used for heart conditions)

Combining Tazzle with nitrates (e.g., nitroglycerin, isosorbide dinitrate) can cause a dangerous drop in blood pressure.

Alpha-Blockers (for blood pressure or prostate issues)

Drugs like tamsulosin or doxazosin can lower blood pressure further when taken with Tazzle.

Other PDE5 Inhibitors

Avoid combining Tadalafil with Sildenafil (Viagra) or Vardenafil (Levitra).

Antibiotics & Antifungals

Medications like erythromycin, ketoconazole, or itraconazole can increase Tadalafil levels in the blood.

HIV Medications

Certain drugs, like ritonavir or saquinavir, can interfere with Tadalafil metabolism.

Blood Thinners

Medications like warfarin may increase the risk of bleeding when combined.

Avoid Alcohol and Grapefruit Juice

Excessive alcohol intake can worsen side effects like dizziness, light-headedness, and hypotension (low blood pressure). Grapefruit Juice may increase Tadalafil levels in the bloodstream, leading to amplified side effects.

Driving and Operating Machinery

Tazzle 20mg can cause dizziness, light-headedness, or blurred vision. Avoid driving, operating heavy machinery, or engaging in tasks that require focus until you know how Tazzle affects you.

Sexual Activity Precaution

Men with cardiovascular conditions should consult their doctor before engaging in sexual activity while using Tazzle, as it can put extra strain on the heart.

Not for Certain Individuals

Tazzle 20mg is not for:

• Women or children, adolescents under 18, and older adults above 64.
• Individuals who are allergic to Tadalafil or any other components in the medication.

While these side effects are mild and resolve within a few hours, consult your healthcare provider if they persist or turn severe.

• Headache
• Flushing (Redness of the Face and Neck)
• Warm sensation or redness
• Dizziness or light-headedness
• Nasal Congestion or Runny Nose
• Indigestion or Heartburn
• Acid reflux or discomfort after meals.
• Back Pain
• Muscle Pain (Myalgia)
• Stomach Upset
• Mild gastrointestinal discomfort
• Blurred Vision or Mild Vision Changes
• Fatigue
• Mild tiredness

Priapism (Prolonged Erection)

An erection that lasts over four hours and is often painful.

Sudden Vision Loss

A rare condition called Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION). Sudden blur vision or complete loss of vision in one or both eyes, difficulty distinguishing colors or seeing details.

Sudden Hearing Loss

Partial or complete hearing loss, sometimes accompanied by ringing in the ears (tinnitus) or dizziness.

Severe Allergic Reactions

Symptoms are swelling of the face, lips, tongue, or throat (angioedema), difficulty breathing or swallowing, severe itching, hives, or skin rashes.

Chest Pain or Heart-Related Issues

Heart problems, including angina or a heart attack, chest pain or tightness, shortness of breath, pain radiating to the jaw, shoulder, or arms, nausea, sweating, or dizziness.

Severe Drop in Blood Pressure (Hypotension)

Low blood pressure may lead to fainting, dizziness or light-headedness, blurred vision, fainting, or loss of consciousness.

Irregular Heartbeat (Arrhythmia)

Symptoms are abnormal heart rhythm or palpitations, fast or irregular heartbeat, chest discomfort, dizziness, or fainting.

Seizures

Uncontrolled shaking or convulsions, loss of awareness or consciousness.

Severe Skin Reactions

Symptoms are Stevens-Johnson Syndrome (SJS), red or purple rash, blisters or peeling skin, and flu-like symptoms before the rash appears.

What is unique about Tazzle 20mg?

Its unique delivery system may benefit individuals with swallowing difficulties and those who prefer faster action than conventional ED tablets.

When to Choose Tazzle 20mg?

Tazzle 20mg is ideal if you are looking for a faster onset of action, convenient, discreet administration, and a cost-effective alternative to branded Tadalafil medications.

When to Be Cautious?

• Side effects persist for a long time.
• Symptoms worsen or become severe.

How do you minimize side effects?

To reduce the chances of experiencing side effects:

• Take Tazzle 20mg with water, preferably after a light meal.
• Avoid alcohol or heavy meals, as they can worsen side effects like dizziness or indigestion.
• Stay hydrated to reduce muscle pain or headaches.

What to Do if Severe Side Effects Occur?

Stop taking Tazzle immediately. Seek emergency medical attention for any severe symptoms. Provide healthcare professionals with details about the medication taken, including dosage.

How to manage Tazzle 20mg Severe Side Effects?

Always follow the medical advice and take the medication responsibly. Do not exceed the recommended dose (20mg once in 24 hours). Avoid combining Tazzle with nitrates, alcohol, or other PDE5 inhibitors. Consult your doctor if you have heart disease, low blood pressure, or eye conditions. Disclose all current medications and health history to your healthcare provider before starting Tazzle.