Generic Antivert contains Meclizine as an active element. It is a prototype non-specific and first generation H1 receptor blocker which is an antihistamine of the piperazine class. Meclizine is a blocker of H1 receptors and does not allow the natural biochemical histamine to show its actions. The mechanism of action of Generic Antivert in vertigo is not related to its anti-histamine properties. When taken during vertigo, it acts as anticholinergic, CNS depressant, and a local anesthetic. Its antiemetic (anti-vomit action) and effects againstvertigo are not yet completely known; yet, anticholinergic actions play a small role in exhibiting these actions. The medication reduces the ear stimulation and internal mechanism that stabilize ear nerve. In straightforward terms it decreases or backs off the ear sensitivity and affects the chemoreceptor trigger zone which is retching focus in the mind. It is utilized as a response to vertigo or emesis (vomiting) and chiefly treats nausea, vomiting, and dizziness which is a resultant of motion sickness. As per the FDA, it is extensively used in management of nausea and vomiting, and dizziness associated with motion sickness and management of vertigo associated with diseases affecting the vestibular system.