Meltabs is a form of Generic Viagra. Hence, it comprises of Sildenafil Citrate as the active ingredient. Sildenafil citrate received approval for the use in treatment of ED by the FDA in the year 1998.
Sildenafil Citrate present in Meltabs belongs to the category of PDE-5 inhibitors. It is the first member of this class and the main-line or gold standard treatment for ED in men. After consumption of Meltabs, sildenafil citrate present in it enters the bloodstream rapidly where it inhibits the action of the enzyme PDE-5. This leads to increase in the blood levels of two biochemicals in the body; viz. nitric oxide (NO) and guanylyl cyclase, which is an enzyme. The augmentation in the levels of the enzymeguanylyl cyclase, in turncauses an upsurge in the levels of cyclic guanosine monophosphate (cGMP) which is a potent vasodilator synthesized in the body near the penile region. The enzyme cGMP then, widens and expands the blood vessels that supply the blood to the penis and also relaxes the muscles beneath the penis. This leads to 2 action which are as follows:
- Enhancement of the blood circulation in the penile region due to widening of the blood vessels
- More blood retained inside the penis and less blood flowing out of the penis due to the relaxation of the smooth muscles present beneath the penis.
- These mechanisms leads to firm and hard as well as long lasting erections for prolonged indulgence in sexual activity.