Malegra FXT is one of the best treatment options to overcome Erectile Dysfunction (ED) and Premature Ejaculation (PE) simultaneously and is very popular among men who suffer from both these issues. It contains two active ingredients viz. Sildenafil Citrate and Duloxetine. Both the active ingredients in Malegra FXT are FDA approved and rendered safe and effective to use and has gained immense popularity due to its inexpensive rates. When Malegra FXT is taken, it mixes with the bloodstream and sildenafil citrate present in it blocks the action of the enzyme PDE-5 in the body. As soon as the PDE5 is inhibited, it upsurges levels of Nitric Oxide and an enzyme called cGMP as high levels of Nitric Oxide are required for proper production of cGMP in the body which is a potent vasodilator. This causes the blood vessels delivering blood to the penis to widen and raises the blood flow into the penis causing the penis to be filled with blood completely. Leads to a hard and sustained erection that lasts for a longer time. The Duloxetine present in Malegra FXT helps in the degradation of the chemical serotonin and leads to a delay in semen ejaculation.