Dapoxetine 60mg Tablets - Dual Treating Medication for Men

Dapoxetine is the active ingredient itself present in the products called Priligy. The mechanism of action of Dapoxetine in premature ejaculation is supposed to be associated to the suppression of neuronal reuptake of serotonin and the successive increase in the effect of the neurotransmitter's action at pre- and post-synaptic receptors. Dapoxetine is known to inhibit the ejaculatory expulsion reflex by acting at a supraspinal level at the specific brain structure for the effect. The neurons that innervate the seminal vesicles, vas deferens, prostate, bulbourethral muscles, and bladder neck cause them to contract in a coordinated fashion to achieve ejaculation. It is known that Dapoxetine might regulate this ejaculatory reflex causing an increase in pudendal motoneuron reflex discharge (PMRD) latency and a reduction in PMRD duration causing a delay in ejaculation.

• Take Generic Priligy as prescribed after consulting a doctor only.
• Do not self-medicateConsume it orally with water .
• Take it roughly an hour before sexual activity. .
• Maintain at least 24 hours between two doses. .
• Ideally the initial dose of this medicine is 30mg.
• Most recommended and commonly available dose of generic Priligy is 60mg..
• Regular use should be avoided .

• Dapoxetine should be used only in men with PE. It does not exhibit ejaculation-delaying effects in men without PE and moreover can lead to excess side-effects.
• Do not use Dapoxetine with recreational drugs. This can lead to arrhythmia, hyperthermia, and serotonin syndrome
• Dapoxetine leads to dizziness, so activities needing mental alertness should be avoided
• Do not consume this medication with alcohol as it may increase the side effects.

Common side effects of Dapoxetine are NOT severe and do not require medical attention. These include:

• Stomach ache
• Fatigue and Weakness
• Anxiety
• Dry mouth
• Chills or sweats
• Swelling
• Headache
• Nasal congestion (Stuffy nose)

These however, require medical attention. These are as follows:

• Increased blood pressure
• Blurred vision
• Giddiness or fainting
• Irregular heart rate
• Austere changes in mood

Which drugs cannot be taken with Dapoxetine

Dapoxetine should be avoided with following medicines:

• Monoamine oxidase inhibitors (MAOIs) which are anti-depressant medications
• Medicine(s) containing thioridazine
• Drugs containing active ingredients like ketoconazole, itraconazole, ritonavir, saquinavir, telithromycin, nefazodone, nelfinavir and atazanavir: Increases the blood levels of Dapoxetine and can lead to toxicity.
• Narcotics and benzodiazepines (can potentiate the effects of dizziness and somnolence)

What should be done in case of Overdose?

• Overdose symptoms are somnolence, nausea and vomiting, increased heart rate, tremor, agitation and dizziness.
• In cases of overdose, normal supportive measures like calling a poison control center or a doctor should be adopted as needed.
• Methods like forced diuresis, dialysis, hemoperfusion and exchange transfusion are not helpful.
• Specific antidotes against Dapoxetine are not yet known

What if a dose of Dapoxetine is missed?

• Consumed the missed dose as soon as you remember
• If the time is near for taking the next dose, avoid the missed dose
• Do not take additional medicine or duple the dose to compensate for the missed dose.
• A gap of 24-hours between two doses is necessary.